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Enzymatic synthesis and phosphorolysis of 4(2)-thioxo- and 6(5)-azapyrimidine nucleosides by E. coli nucleoside phosphorylases
The trans-2-deoxyribosylation of 4-thiouracil ((4S)Ura) and 2-thiouracil ((2S)Ura), as well as 6-azauracil, 6-azathymine and 6-aza-2-thiothymine was studied using dG and E. coli purine nucleoside phosphorylase (PNP) for the in situ generation of 2-deoxy-α-D-ribofuranose-1-phosphate (dRib-1P) followe...
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| Pubblicato in: | Beilstein J Org Chem |
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| Autori principali: | , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Beilstein-Institut
2016
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5238616/ https://ncbi.nlm.nih.gov/pubmed/28144328 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3762/bjoc.12.254 |
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