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A detailed view on 1,8-cineol biosynthesis by Streptomyces clavuligerus

The stereochemical course of the cyclisation reaction catalysed by the bacterial 1,8-cineol synthase from Streptomyces clavuligerus was investigated using stereospecifically deuterated substrates. In contrast to the well investigated plant enzyme from Salvia officinalis, the reaction proceeds via (S...

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Bibliographic Details
Published in:Beilstein J Org Chem
Main Authors: Rinkel, Jan, Rabe, Patrick, zur Horst, Laura, Dickschat, Jeroen S
Format: Artigo
Language:Inglês
Published: Beilstein-Institut 2016
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5238540/
https://ncbi.nlm.nih.gov/pubmed/28144299
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3762/bjoc.12.225
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