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Thymidylate limitation potentiates cephalosporin activity towards enterococci via an exopolysaccharide-based mechanism

Multi-drug resistant enterococci are major causes of nosocomial infections. Prior therapy with cephalosporins increases the risk of developing an enterococcal infection due to the intrinsic resistance of enterococci to these antibiotics. While progress has been made towards understanding the genetic...

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Publicat a:ACS Chem Biol
Autors principals: Hoff, Jessica S., Kristich, Christopher J.
Format: Artigo
Idioma:Inglês
Publicat: 2016
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5238413/
https://ncbi.nlm.nih.gov/pubmed/27008338
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acschembio.5b01041
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