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Genetic Basis for Vancomycin-Enhanced Cephalosporin Susceptibility in Vancomycin-Resistant Enterococci Revealed Using Counterselection with Dominant-Negative Thymidylate Synthase

Antibiotic-resistant enterococci are major causes of hospital-acquired infections. All enterococci are intrinsically resistant to most cephalosporins, antibiotics in the beta-lactam family that impair peptidoglycan synthesis by inactivating the transpeptidases responsible for cross-linking. In addit...

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Detalhes bibliográficos
Main Authors: Kristich, Christopher J., Djorić, Dušanka, Little, Jaime L.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3957902/
https://ncbi.nlm.nih.gov/pubmed/24366749
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.02001-13
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