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3-deoxyschweinfurthin B lowers cholesterol levels by decreasing synthesis and increasing export in cultured cancer cell lines

The schweinfurthins have potent antiproliferative activity in multiple glioblastoma multiforme (GBM) cell lines; however, the mechanism by which growth is impeded is not fully understood. Previously, we demonstrated that the schweinfurthins reduce the level of key isoprenoid intermediates in the cho...

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Detalhes bibliográficos
Publicado no:Lipids
Main Authors: Kuder, Craig H., Weivoda, Megan M., Zhang, Ying, Zhu, Junjia, Neighbors, Jeffrey D., Wiemer, David F., Hohl, Raymond J.
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5238408/
https://ncbi.nlm.nih.gov/pubmed/26494560
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11745-015-4083-z
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