Adrenomedullin promotes angiogenesis in epithelial ovarian cancer through upregulating hypoxia-inducible factor-1α and vascular endothelial growth factor

Adrenomedullin (ADM) is a multi-functional peptide related to many kinds of tumors. This study was aimed to investigate the role of ADM on angiogenesis in epithelial ovarian cancer (EOC) and its possible mechanism. The expressions of ADM, vascular endothelial growth factor (VEGF), hypoxia-inducible...

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Veröffentlicht in:Sci Rep
Hauptverfasser: Zhang, Yi, Xu, Yang, Ma, Jian, Pang, Xiaoyan, Dong, Mei
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group 2017
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5238385/
https://ncbi.nlm.nih.gov/pubmed/28091613
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep40524
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