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Molecular mechanisms of bio-catalysis of heme extraction from hemoglobin
Red blood cell hemolysis in sickle cell disease (SCD) releases free hemoglobin. Extracellular hemoglobin and its degradation products, free heme and iron, are highly toxic due to oxidative stress induction and decrease in nitric oxide availability. We propose an approach that helps to eliminate extr...
Na minha lista:
| Foilsithe in: | Redox Biol |
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| Main Authors: | , , , |
| Formáid: | Artigo |
| Teanga: | Inglês |
| Foilsithe: |
Elsevier
2017
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| Ábhair: | |
| Rochtain Ar Líne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5237811/ https://ncbi.nlm.nih.gov/pubmed/28088643 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.redox.2017.01.004 |
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