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Mechanistic studies on depurination and apurinic site chain breakage in oligodeoxyribonucleotides.
Products formed from defined oligodeoxyribonucleotide tetramers (oligonucleotides) by depurination at pH 5.0 and 90 degrees C followed by chain breakage at the resulting apurinic sites (AP sites) were assigned by reversed phase HPLC. Through kinetic analysis, rate constants of depurination and subse...
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| Autores principales: | , , |
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| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
1994
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| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC523769/ https://ncbi.nlm.nih.gov/pubmed/7800492 |
| Etiquetas: |
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