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Optimizing k-mer size using a variant grid search to enhance de novo genome assembly

Largely driven by huge reductions in per-base costs, sequencing nucleic acids has become a near-ubiquitous technique in laboratories performing biological and biomedical research. Most of the effort goes to re-sequencing, but assembly of de novogenerated, raw sequence reads into contigs that span as...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Bioinformation
Hauptverfasser: Cha, Soyeon, Bird, David McK
Format: Artigo
Sprache:Inglês
Veröffentlicht: Biomedical Informatics 2016
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5237644/
https://ncbi.nlm.nih.gov/pubmed/28104957
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.6026/97320630012036
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