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HyDA-Vista: towards optimal guided selection of k-mer size for sequence assembly

MOTIVATION: Intimately tied to assembly quality is the complexity of the de Bruijn graph built by the assembler. Thus, there have been many paradigms developed to decrease the complexity of the de Bruijn graph. One obvious combinatorial paradigm for this is to allow the value of k to vary; having a...

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Veröffentlicht in:BMC Genomics
Hauptverfasser: Shariat, Basir, Movahedi, Narjes Sadat, Chitsaz, Hamidreza, Boucher, Christina
Format: Artigo
Sprache:Inglês
Veröffentlicht: BioMed Central 2014
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4304221/
https://ncbi.nlm.nih.gov/pubmed/25558875
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2164-15-S10-S9
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