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Expression of the E. coli fpg gene in mammalian cells reduces the mutagenicity of gamma-rays.

The E. coli fpg gene encodes the formamido-pyrimidine-DNA-glycosylase (FPG protein) which specifically removes the formamido-pyrimidine and C8-oxoGuanine residues from gamma-irradiated DNA. The fpg gene was ligated in the psV2 vector and transfected into the Chinese hamster CHO and V-79 cells. The t...

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Bibliographische Detailangaben
1. Verfasser: Laval, F
Format: Artigo
Sprache:Inglês
Veröffentlicht: 1994
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC523760/
https://ncbi.nlm.nih.gov/pubmed/7800484
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