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Guidance for the utility of linear models in meta-analysis of genetic association studies of binary phenotypes
Linear mixed models are increasingly used for the analysis of genome-wide association studies (GWAS) of binary phenotypes because they can efficiently and robustly account for population stratification and relatedness through inclusion of random effects for a genetic relationship matrix. However, th...
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| Published in: | Eur J Hum Genet |
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| Main Authors: | , , |
| Format: | Artigo |
| Language: | Inglês |
| Published: |
Nature Publishing Group
2017
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5237383/ https://ncbi.nlm.nih.gov/pubmed/27848946 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ejhg.2016.150 |
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