Protective Efficacy of Multiple Vaccine Platforms Against Zika Virus Challenge in Rhesus Monkeys

Zika virus (ZIKV) is responsible for a major ongoing epidemic in the Americas and has been causally associated with fetal microcephaly. The development of a safe and effective ZIKV vaccine is therefore an urgent global health priority. Here we demonstrate that three different vaccine platforms prote...

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Veröffentlicht in:Science
Hauptverfasser: Abbink, Peter, Larocca, Rafael A., De La Barrera, Rafael A., Bricault, Christine A., Moseley, Edward T., Boyd, Michael, Kirilova, Marinela, Li, Zhenfeng, Ng’ang’a, David, Nanayakkara, Ovini, Nityanandam, Ramya, Mercado, Noe B., Borducchi, Erica N., Agarwal, Arshi, Brinkman, Amanda L., Cabral, Crystal, Chandrashekar, Abishek, Giglio, Patricia B., Jetton, David, Jimenez, Jessica, Lee, Benjamin C., Mojta, Shanell, Molloy, Katherine, Shetty, Mayuri, Neubauer, George H., Stephenson, Kathryn E., Peron, Jean Pierre S., Zanotto, Paolo M. de A., Misamore, Johnathan, Finneyfrock, Brad, Lewis, Mark G., Alter, Galit, Modjarrad, Kayvon, Jarman, Richard G., Eckels, Kenneth H., Michael, Nelson L., Thomas, Stephen J., Barouch, Dan H.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2016
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5237380/
https://ncbi.nlm.nih.gov/pubmed/27492477
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.aah6157
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