Diverse roles of assembly factors revealed by structures of late nuclear pre-60S ribosomes

Ribosome biogenesis is a highly complex process in eukaryotes, involving temporally and spatially regulated ribosomal protein (r-protein) binding and ribosomal RNA remodelling events in the nucleolus, nucleoplasm and cytoplasm(1,2). Hundreds of assembly factors, organized into sequential functional...

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Detalhes bibliográficos
Publicado no:Nature
Main Authors: Wu, Shan, Tutuncuoglu, Beril, Yan, Kaige, Brown, Hailey, Zhang, Yixiao, Tan, Dan, Gamalinda, Michael, Yuan, Yi, Li, Zhifei, Jakovljevic, Jelena, Ma, Chengying, Lei, Jianlin, Dong, Meng-Qiu, Woolford, John L., Gao, Ning
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5237361/
https://ncbi.nlm.nih.gov/pubmed/27251291
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature17942
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