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Coupling of 5S RNP rotation with maturation of functional centers during large ribosomal subunit assembly

The protein composition and structure of assembling 60S ribosomal subunits undergo numerous changes as pre-ribosomes transition from the nucleolus to the nucleoplasm. This includes stable anchoring of the Rpf2 subcomplex containing 5S rRNA, rpL5, rpL11, Rpf2 and Rrs1, which initially docks onto the...

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Veröffentlicht in:Nat Commun
Hauptverfasser: Micic, Jelena, Li, Yu, Wu, Shan, Wilson, Daniel, Tutuncuoglu, Beril, Gao, Ning, Woolford, John L.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group UK 2020
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7385084/
https://ncbi.nlm.nih.gov/pubmed/32719344
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-020-17534-5
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