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Minor groove contacts are essential for an interaction of the human cytomegalovirus IE2 protein with its DNA target.

The 86 kDa immediate early-2 protein (IE2, IE86) of human cytomegalovirus (HCMV) is a multifunctional polypeptide that can regulate gene expression both positively and negatively. In particular, it represses its own mRNA synthesis by binding directly to a sequence element, termed cis repression sign...

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Bibliografische gegevens
Hoofdauteurs: Lang, D, Stamminger, T
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 1994
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC523726/
https://ncbi.nlm.nih.gov/pubmed/8078768
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