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Minor groove contacts are essential for an interaction of the human cytomegalovirus IE2 protein with its DNA target.
The 86 kDa immediate early-2 protein (IE2, IE86) of human cytomegalovirus (HCMV) is a multifunctional polypeptide that can regulate gene expression both positively and negatively. In particular, it represses its own mRNA synthesis by binding directly to a sequence element, termed cis repression sign...
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| Auteurs principaux: | , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
1994
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| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC523726/ https://ncbi.nlm.nih.gov/pubmed/8078768 |
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