Trinitrobenzene Sulfonic Acid-induced Intestinal Injury in Neonatal Mice Activates Transcriptional Networks Similar to those seen in Human Necrotizing Enterocolitis

BACKGROUND: We have shown previously that enteral administration of 2, 4, 6-trinitrobenzene sulfonic acid in 10-day-old C57BL/6 pups produces an acute necrotizing enterocolitis with histopathological and inflammatory changes similar to human necrotizing enterocolitis (NEC). To determine whether muri...

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Publicat a:Pediatr Res
Autors principals: MohanKumar, Krishnan, Namachivayam, Kopperuncholan, Cheng, Feng, Jiang, Rays H. Y., Flores-Torres, Jaime, Torres, Benjamin A., Maheshwari, Akhil
Format: Artigo
Idioma:Inglês
Publicat: 2016
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5235988/
https://ncbi.nlm.nih.gov/pubmed/27656771
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/pr.2016.189
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