Targeted inhibition of thrombin attenuates murine neonatal necrotizing enterocolitis

Necrotizing enterocolitis (NEC) is an inflammatory bowel necrosis of premature infants and an orphan disease with no specific treatment. Most patients with confirmed NEC develop moderate-severe thrombocytopenia requiring one or more platelet transfusions. Here we used our neonatal murine model of NE...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Proc Natl Acad Sci U S A
Egile Nagusiak: Namachivayam, Kopperuncholan, MohanKumar, Krishnan, Shores, Darla R., Jain, Sunil K., Fundora, Jennifer, Everett, Allen D., He, Ling, Pan, Hua, Wickline, Samuel A., Maheshwari, Akhil
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: National Academy of Sciences 2020
Gaiak:
Biological Sciences
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC7245134/
https://ncbi.nlm.nih.gov/pubmed/32366656
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1912357117
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