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Mutations in the peptidyl transferase region of E. coli 23S rRNA affecting translational accuracy.

We have produced mutations in a cloned Escherichia coli 23S rRNA gene at positions G2252 and G2253. These sites are protected in chemical footprinting studies by the 3' terminal CCA of P site-bound tRNA. Three possible base changes were introduced at each position and the mutations produced a r...

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Detalhes bibliográficos
Publicado no:Nucleic Acids Res
Main Authors: Gregory, S T, Lieberman, K R, Dahlberg, A E
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 1994
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC523577/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8127663/
https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/22.3.279
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