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CENP-A modifications on Ser68 and Lys124 are dispensable for establishment, maintenance, and long-term function of human centromeres

CENP-A is a histone H3 variant key to epigenetic specification of mammalian centromeres. Using transient overexpression of CENP-A mutants, two recent reports in Developmental Cell proposed essential centromere functions for post-translational modifications of human CENP-A. Phosphorylation at Ser68 w...

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Detalhes bibliográficos
Publicado no:Dev Cell
Main Authors: Fachinetti, Daniele, Logsdon, Glennis A., Abdullah, Amira, Selzer, Evan B., Cleveland, Don W., Black, Ben E.
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5235356/
https://ncbi.nlm.nih.gov/pubmed/28073008
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.devcel.2016.12.014
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