Repression of the interleukin 6 gene promoter by p53 and the retinoblastoma susceptibility gene product.
The aberrant overexpression of interleukin 6 (IL-6) is implicated as an autocrine mechanism in the enhanced proliferation of the neoplastic cell elements in various B- and T-cell malignancies and in some carcinomas and sarcomas; many of these neoplasms have been shown to be associated with a mutated...
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| Publicado no: | Proc Natl Acad Sci U S A |
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| Principais autores: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
1991
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC52350/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1652755/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.88.17.7605 |
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