HTLV-1 bZIP Factor Enhances T-Cell Proliferation by Impeding the Suppressive Signaling of Co-inhibitory Receptors

Human T-cell leukemia virus type 1 (HTLV-1) causes adult T-cell leukemia-lymphoma (ATL) and inflammatory diseases. To enhance cell-to-cell transmission of HTLV-1, the virus increases the number of infected cells in vivo. HTLV-1 bZIP factor (HBZ) is constitutively expressed in HTLV-1 infected cells a...

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Publicado en:PLoS Pathog
Autores principales: Kinosada, Haruka, Yasunaga, Jun-ichirou, Shimura, Kazuya, Miyazato, Paola, Onishi, Chiho, Iyoda, Tomonori, Inaba, Kayo, Matsuoka, Masao
Formato: Artigo
Lenguaje:Inglês
Publicado: Public Library of Science 2017
Materias:
Research Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5234849/
https://ncbi.nlm.nih.gov/pubmed/28046066
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1006120
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