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Interferon-γ Promotes Inflammation and Development of T-Cell Lymphoma in HTLV-1 bZIP Factor Transgenic Mice

Human T-cell leukemia virus type 1 (HTLV-1) is an etiological agent of several inflammatory diseases and a T-cell malignancy, adult T-cell leukemia (ATL). HTLV-1 bZIP factor (HBZ) is the only viral gene that is constitutively expressed in HTLV-1-infected cells, and it has multiple functions on T-cel...

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Detalhes bibliográficos
Publicado no:PLoS Pathog
Principais autores: Mitagami, Yu, Yasunaga, Jun-ichirou, Kinosada, Haruka, Ohshima, Koichi, Matsuoka, Masao
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4546626/
https://ncbi.nlm.nih.gov/pubmed/26296091
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1005120
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