Leptin-Induced Endothelium-Independent Vasoconstriction in Thoracic Aorta and Pulmonary Artery of Spontaneously Hypertensive Rats: Role of Calcium Channels and Stores

Decreased leptin-induced endothelium-dependent vasodilation has been reported in spontaneously hypertensive rats (SHR). Here, we report leptin-induced vasoconstriction in endothelium-denuded pulmonary artery and thoracic aorta from SHR and sought to characterize calcium handling underlying these mec...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Gomart, Samantha, Gaudreau-Ménard, Caroline, Jespers, Pascale, Dilek, Omer Gurkan, Hupkens, Emeline, Hanthazi, Aliénor, Naeije, Robert, Melot, Christian, Labranche, Nathalie, Dewachter, Laurence, Mc Entee, Kathleen
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2017
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5234800/
https://ncbi.nlm.nih.gov/pubmed/28085954
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0169205
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