Oxidized high density lipoprotein induces macrophage apoptosis via toll-like receptor 4-dependent CHOP pathway

Oxidized HDL (ox-HDL), unlike native HDL that exerts antiatherogenic effects, plays a proatherogenic role. However, the underlying mechanisms are not completely understood. This study was designed to explore the inductive effect of ox-HDL on endoplasmic reticulum (ER) stress-CCAAT-enhancer-binding p...

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Detalhes bibliográficos
Publicado no:J Lipid Res
Main Authors: Yao, Shutong, Tian, Hua, Zhao, Li, Li, Jinguo, Yang, Libo, Yue, Feng, Li, Yanyan, Jiao, Peng, Yang, Nana, Wang, Yiwei, Zhang, Xiangjian, Qin, Shucun
Formato: Artigo
Idioma:Inglês
Publicado em: The American Society for Biochemistry and Molecular Biology 2017
Assuntos:
Research Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5234716/
https://ncbi.nlm.nih.gov/pubmed/27895089
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1194/jlr.M071142
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