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D4F alleviates macrophage-derived foam cell apoptosis by inhibiting CD36 expression and ER stress-CHOP pathway

This study was designed to explore the protective effect of D4F, an apoA-I mimetic peptide, on oxidized LDL (ox-LDL)-induced endoplasmic reticulum (ER) stress-CCAAT/enhancer-binding protein (C/EBP) homologous protein (CHOP) pathway-mediated apoptosis in macrophages. Our results showed that treating...

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Détails bibliographiques
Publié dans:J Lipid Res
Auteurs principaux: Yao, Shutong, Tian, Hua, Miao, Cheng, Zhang, Da-Wei, Zhao, Li, Li, Yanyan, Yang, Nana, Jiao, Peng, Sang, Hui, Guo, Shoudong, Wang, Yiwei, Qin, Shucun
Format: Artigo
Langue:Inglês
Publié: The American Society for Biochemistry and Molecular Biology 2015
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4373741/
https://ncbi.nlm.nih.gov/pubmed/25635126
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1194/jlr.M055400
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