Endoplasmic Reticulum Stress Promotes Macrophage-derived Foam Cell Formation by Up-regulating Cluster of Differentiation 36 (CD36) Expression

Oxidized low-density lipoprotein (ox-LDL) up-regulates CD36, a scavenger receptor responsible for macrophage uptake of ox-LDL without limitation. However, the precise underlying mechanism is not completely understood. Our previous study has demonstrated that ox-LDL induces endoplasmic reticulum (ER)...

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Detalhes bibliográficos
Main Authors: Yao, Shutong, Miao, Cheng, Tian, Hua, Sang, Hui, Yang, Nana, Jiao, Peng, Han, Jiju, Zong, Chuanlong, Qin, Shucun
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2014
Assuntos:
Cell Biology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3924270/
https://ncbi.nlm.nih.gov/pubmed/24366867
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M113.524512
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