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Nicotinic acid timed to feeding reverses tissue lipid accumulation and improves glucose control in obese Zucker rats([S])

Nicotinic acid (NiAc) is a potent inhibitor of lipolysis, acutely reducing plasma free fatty acid (FFA) concentrations. However, a major FFA rebound is seen during rapid NiAc washout, and sustained exposure is associated with tolerance development, with FFAs returning to pretreatment levels. Our aim...

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Detalhes bibliográficos
Publicado no:J Lipid Res
Main Authors: Kroon, Tobias, Baccega, Tania, Olsén, Arne, Gabrielsson, Johan, Oakes, Nicholas D.
Formato: Artigo
Idioma:Inglês
Publicado em: The American Society for Biochemistry and Molecular Biology 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5234709/
https://ncbi.nlm.nih.gov/pubmed/27875257
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1194/jlr.M068395
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