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Nicotinic acid timed to feeding reverses tissue lipid accumulation and improves glucose control in obese Zucker rats([S])
Nicotinic acid (NiAc) is a potent inhibitor of lipolysis, acutely reducing plasma free fatty acid (FFA) concentrations. However, a major FFA rebound is seen during rapid NiAc washout, and sustained exposure is associated with tolerance development, with FFAs returning to pretreatment levels. Our aim...
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Publicado no: | J Lipid Res |
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Main Authors: | , , , , |
Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
The American Society for Biochemistry and Molecular Biology
2017
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5234709/ https://ncbi.nlm.nih.gov/pubmed/27875257 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1194/jlr.M068395 |
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