Joint Feedback Analysis Modeling of Nonesterified Fatty Acids in Obese Zucker Rats and Normal Sprague–Dawley Rats after Different Routes of Administration of Nicotinic Acid

Data were pooled from several studies on nicotinic acid (NiAc) intervention of fatty acid turnover in normal Sprague–Dawley and obese Zucker rats in order to perform a joint PKPD of data from more than 100 normal Sprague–Dawley and obese Zucker rats, exposed to several administration routes and rate...

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Detalhes bibliográficos
Publicado no:J Pharm Sci
Main Authors: Tapani, Sofia, Almquist, Joachim, Leander, Jacob, Ahlström, Christine, Peletier, Lambertus A, Jirstrand, Mats, Gabrielsson, Johan
Formato: Artigo
Idioma:Inglês
Publicado em: BlackWell Publishing Ltd 2014
Assuntos:
Pharmacokinetics, Pharmacodynamics and Drug Transport and Metabolism
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4303919/
https://ncbi.nlm.nih.gov/pubmed/24986056
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jps.24077
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