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Effects of Zacopride, a Moderate I(K1) channel agonist, on Triggered Arrhythmia and Contractility in Human Ventricular Myocardium

Ventricular tachycardia is the leading cause of sudden arrhythmic death in the U.S. Recently, the moderate I(K1) channel activator, zacopride, was shown to suppress triggered ventricular tachycardia in rats. Nonetheless, concerns were raised about the possibility of pro-arrhythmic activity after I(K...

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Detalhes bibliográficos
Publicado no:Pharmacol Res
Main Authors: Elnakish, Mohammad T., Canan, Benjamin D., Kilic, Ahmet, Mohler, Peter J., Janssen, Paul M. L.
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5234043/
https://ncbi.nlm.nih.gov/pubmed/27914945
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.phrs.2016.11.033
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