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ON or OFF?: Modulating the N-Methyl-D-Aspartate Receptor in Major Depression

Since the discovery that a single dose of ketamine, an N-methyl-D-aspartate receptor (NMDAR) antagonist, had rapid and long-lasting antidepressant effects, there has been increased interest in using NMDAR modulators in the pharmacotherapy of depression. Ketamine’s efficacy seems to imply that depres...

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Dades bibliogràfiques
Publicat a:Front Mol Neurosci
Autors principals: Chan, Shi Yu, Matthews, Edward, Burnet, Philip W. J.
Format: Artigo
Idioma:Inglês
Publicat: Frontiers Media S.A. 2017
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5233677/
https://ncbi.nlm.nih.gov/pubmed/28133445
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fnmol.2016.00169
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