The Chlamydia trachomatis inclusion membrane protein CpoS counteracts STING-mediated cellular surveillance and suicide programs

Evading cell death is critical for Chlamydia to maintain a replicative niche but the underlying mechanisms are unknown. We screened a library of Chlamydia mutants for modulators of cell death. Inactivation of the inclusion membrane protein CpoS (Chlamydia promoter of Survival) induced rapid apoptoti...

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Publicado en:Cell Host Microbe
Main Authors: Sixt, Barbara S., Bastidas, Robert J., Finethy, Ryan, Baxter, Ryan M., Carpenter, Victoria K., Kroemer, Guido, Coers, Jörn, Valdivia, Raphael H.
Formato: Artigo
Idioma:Inglês
Publicado: 2016
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Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5233594/
https://ncbi.nlm.nih.gov/pubmed/28041929
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.chom.2016.12.002
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