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Exploring structural motifs necessary for substrate binding in the active site of Escherichia coli pantothenate kinase
The coenzyme A (CoA) biosynthetic enzymes have been used to produce various CoA analogues, including mechanistic probes of CoA-dependent enzymes such as those involved in fatty acid biosynthesis. These enzymes are also important for the activation of the pantothenamide class of antibacterial agents,...
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| Publicado no: | Bioorg Med Chem |
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| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5233448/ https://ncbi.nlm.nih.gov/pubmed/24814884 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bmc.2014.04.030 |
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