Ubiquitination of Human T-Cell Leukemia Virus Type 1 Tax Modulates Its Activity

Human T-cell leukemia virus type 1 (HTLV-1) encodes a 40-kDa Tax phosphoprotein. Tax is a transcriptional activator which modulates expression of the viral long terminal repeat and transcription of many cellular genes. Because Tax is a critical HTLV-1 factor which mediates viral transformation of T...

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Bibliographic Details
Main Authors: Peloponese, Jean-Marie, Iha, Hidekatsu, Yedavalli, Venkat R. K., Miyazato, Akiko, Li, Yan, Haller, Kerstin, Benkirane, Monsef, Jeang, Kuan-Teh
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 2004
Subjects:
Replication
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC523283/
https://ncbi.nlm.nih.gov/pubmed/15479810
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.78.21.11686-11695.2004
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