NF-kappaB activation: Tax sumoylation is out, but what about Tax ubiquitination?

<p>Abstract</p> <p>Activation of the NF-κB transcription factors by the viral protein Tax plays a vital role in the pathogenesis of diseases associated with human T-cell lymphotropic virus type I (HTLV-I). The Tax oncoprotein undergoes constitutive K63-linked ubiquitination and sumoylation; however,...

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Autor principal:	Xiao Gutian
Formato:	Artigo
Lenguaje:	Inglês
Publicado:	BMC 2012-09-01
Colección:	Retrovirology
Materias:	ATL IKK HTLV Leukemia NF-κB Nuclear body Retrovirus SUMO Tax Taxisome Tumroigenesis Ubiquitin
Acceso en línea:	http://www.retrovirology.com/content/9/1/78
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