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Between-Host Evolution of Cytotoxic T-Lymphocyte Epitopes in Human Immunodeficiency Virus Type 1: an Approach Based on Phylogenetically Independent Comparisons

In human immunodeficiency virus type 1 (HIV-1), mutations that escape from cytotoxic T-lymphocyte (CTL) recognition have been documented, and sequence analyses have provided indirect support for the hypothesis that natural selection has favored CTL escape mutants within an infected host. In spite of...

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Détails bibliographiques
Auteurs principaux: Piontkivska, Helen, Hughes, Austin L.
Format: Artigo
Langue:Inglês
Publié: American Society for Microbiology 2004
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC523241/
https://ncbi.nlm.nih.gov/pubmed/15479817
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.78.21.11758-11765.2004
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