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The Putative Zinc Finger of the Human Cytomegalovirus IE2 86-Kilodalton Protein Is Dispensable for DNA Binding and Autorepression, Thereby Demarcating a Concise Core Domain in the C Terminus of the Protein

The IE2 86-kDa gene product is an essential regulatory protein of human cytomegalovirus (HCMV) with several functions, including transactivation, negative autoregulation, and cell cycle regulation. In order to understand the physiological significance of each of the IE2 functions, discriminating mut...

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Detalhes bibliográficos
Main Authors: Asmar, Jasmin, Wiebusch, Lüder, Truss, Matthias, Hagemeier, Christian
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2004
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC523240/
https://ncbi.nlm.nih.gov/pubmed/15479827
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.78.21.11853-11864.2004
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