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SUMOylation of the Human Cytomegalovirus 72-Kilodalton IE1 Protein Facilitates Expression of the 86-Kilodalton IE2 Protein and Promotes Viral Replication

The 72-kDa immediate-early 1 protein (IE1-72kDa) of human cytomegalovirus has been previously shown to be posttranslationally modified by covalent conjugation to the ubiquitin-related protein SUMO-1. Using an infectious bacterial artificial chromosome clone of human cytomegalovirus, we constructed a...

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Detalhes bibliográficos
Main Authors: Nevels, Michael, Brune, Wolfram, Shenk, Thomas
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2004
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC434104/
https://ncbi.nlm.nih.gov/pubmed/15220454
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.78.14.7803-7812.2004
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