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SUMOylation of the Human Cytomegalovirus 72-Kilodalton IE1 Protein Facilitates Expression of the 86-Kilodalton IE2 Protein and Promotes Viral Replication

The 72-kDa immediate-early 1 protein (IE1-72kDa) of human cytomegalovirus has been previously shown to be posttranslationally modified by covalent conjugation to the ubiquitin-related protein SUMO-1. Using an infectious bacterial artificial chromosome clone of human cytomegalovirus, we constructed a...

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Bibliografiske detaljer
Udgivet i:J Virol
Principais autores: Nevels, Michael, Brune, Wolfram, Shenk, Thomas
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology (ASM) 2004
Fag:
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC434104/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/15220454/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/JVI.78.14.7803-7812.2004
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