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Extinction Training Regulates Neuroadaptive Responses to Withdrawal from Chronic Cocaine Self-Administration

Cocaine produces multiple neuroadaptations with chronic repeated use. Many of these neuroadaptations can be reversed or normalized by extinction training during withdrawal from chronic cocaine self-administration in rats. This article reviews our past and present studies on extinction-induced modula...

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Main Authors: Self, David W., Choi, Kwang-Ho, Simmons, Diana, Walker, John R., Smagula, Cynthia S.
Format: Artigo
Jezik:Inglês
Izdano: Cold Spring Harbor Laboratory Press 2004
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC523085/
https://ncbi.nlm.nih.gov/pubmed/15466321
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/lm.81404
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