Definition of Human Epitopes Recognized in Tetanus Toxoid and Development of an Assay Strategy to Detect Ex Vivo Tetanus CD4(+) T Cell Responses

Despite widespread uses of tetanus toxoid (TT) as a vaccine, model antigen and protein carrier, TT epitopes have been poorly characterized. Herein we defined the human CD4(+) T cell epitope repertoire by reevaluation of previously described epitopes and evaluation of those derived from prediction of...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: da Silva Antunes, Ricardo, Paul, Sinu, Sidney, John, Weiskopf, Daniela, Dan, Jennifer M., Phillips, Elizabeth, Mallal, Simon, Crotty, Shane, Sette, Alessandro, Lindestam Arlehamn, Cecilia S.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2017
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5230748/
https://ncbi.nlm.nih.gov/pubmed/28081174
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0169086
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