LcrV Synthesis Is Altered by DNA Adenine Methylase Overproduction in Yersinia pseudotuberculosis and Is Required To Confer Immunity in Vaccinated Hosts

Yersinia pseudotuberculosis mutants that overproduce the DNA adenine methylase (Dam(OP) Yersinia) are attenuated, confer robust protective immune responses, and synthesize or secrete several Yersinia outer proteins (Yops) under conditions that are nonpermissive for synthesis and secretion in wild-ty...

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Bibliographic Details
Main Authors: Badie, Golnaz, Heithoff, Douglas M., Mahan, Michael J.
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 2004
Subjects:
Microbial Immunity and Vaccines
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC523050/
https://ncbi.nlm.nih.gov/pubmed/15501808
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.72.11.6707-6710.2004
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