DNA Adenine Methylase Is Essential for Viability and Plays a Role in the Pathogenesis of Yersinia pseudotuberculosis and Vibrio cholerae

Salmonella strains that lack or overproduce DNA adenine methylase (Dam) elicit a protective immune response to different Salmonella species. To generate vaccines against other bacterial pathogens, the dam genes of Yersinia pseudotuberculosis and Vibrio cholerae were disrupted but found to be essenti...

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Autors principals: Julio, Steven M., Heithoff, Douglas M., Provenzano, Daniele, Klose, Karl E., Sinsheimer, Robert L., Low, David A., Mahan, Michael J.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology 2001
Matèries:
Molecular Pathogenesis
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC98854/
https://ncbi.nlm.nih.gov/pubmed/11705940
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.69.12.7610-7615.2001
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