Molecular characterization of severe hemophilia A suggests that about half the mutations are not within the coding regions and splice junctions of the factor VIII gene.

Ítems similars

• Partial correction of a severe molecular defect in hemophilia A, because of errors during expression of the factor VIII gene.
  per: Young, M, et al.
  Publicat: (1997)
• Moderately severe hemophilia A resulting from Glu----Gly substitution in exon 7 of the factor VIII gene.
  per: Youssoufian, H, et al.
  Publicat: (1988)
• Hemophilia A due to mutations that create new N-glycosylation sites.
  per: Aly, A M, et al.
  Publicat: (1992)
• A novel missense mutation in the factor VIII gene identified by analysis of amplified hemophilia DNA sequences.
  per: Levinson, B, et al.
  Publicat: (1987)
• Molecular characterization of mild-to-moderate hemophilia A: detection of the mutation in 25 of 29 patients by denaturing gradient gel electrophoresis.
  per: Higuchi, M, et al.
  Publicat: (1991)