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Moderately severe hemophilia A resulting from Glu----Gly substitution in exon 7 of the factor VIII gene.
To define the molecular basis of a TaqI site alteration in the factor VIII gene of a patient with moderately severe hemophilia A, we used a combination of genomic amplification followed by direct sequencing and oligonucleotide hybridization, to demonstrate an A-to-G substitution in exon 7 (codon 291...
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| Main Authors: | , , , , , |
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| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
1988
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1715196/ https://ncbi.nlm.nih.gov/pubmed/2835904 |
| Oznake: |
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