Cyclic GMP-dependent protein kinase II is a molecular switch from proliferation to hypertrophic differentiation of chondrocytes

The Komeda miniature rat Ishikawa (KMI) is a naturally occurring mutant caused by an autosomal recessive mutation mri, which exhibits longitudinal growth retardation. Here we identified the mri mutation as a deletion in the rat gene encoding cGMP-dependent protein kinase type II (cGKII). KMIs showed...

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Detalhes bibliográficos
Main Authors: Chikuda, Hirotaka, Kugimiya, Fumitaka, Hoshi, Kazuto, Ikeda, Toshiyuki, Ogasawara, Toru, Shimoaka, Takashi, Kawano, Hirotaka, Kamekura, Satoru, Tsuchida, Atsuko, Yokoi, Norihide, Nakamura, Kozo, Komeda, Kajuro, Chung, Ung-il, Kawaguchi, Hiroshi
Formato: Artigo
Idioma:Inglês
Publicado em: Cold Spring Harbor Laboratory Press 2004
Assuntos:
Research Papers
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC522991/
https://ncbi.nlm.nih.gov/pubmed/15466490
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.1224204
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