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Rapid Detection of Common HIV-1 Drug Resistance Mutations by Use of High-Resolution Melting Analysis and Unlabeled Probes

HIV rapidly accumulates resistance mutations following exposure to subtherapeutic concentrations of antiretroviral drugs that reduces treatment efficacy. High-resolution melting analysis (HRMA) has been used to successfully identify single nucleotide polymorphisms (SNPs) and to genotype viral and ba...

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Detalhes bibliográficos
Publicado no:J Clin Microbiol
Main Authors: Sacks, David, Ledwaba, Johanna, Morris, Lynn, Hunt, Gillian M.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5228223/
https://ncbi.nlm.nih.gov/pubmed/27795333
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JCM.01291-16
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