Non-linear impact of glutathione depletion on C. elegans life span and stress resistance

The redox environment in cells and organisms is set by low-molecular mass and protein-bound thiols, with glutathione (GSH) representing a major intracellular redox buffer. Subtle thiol oxidation elicits signal transduction processes and adaptive responses to cope with stressors, whereas highly oxidi...

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Bibliographic Details
Published in:Redox Biol
Main Authors: Urban, Nadine, Tsitsipatis, Dimitrios, Hausig, Franziska, Kreuzer, Katrin, Erler, Katrin, Stein, Vanessa, Ristow, Michael, Steinbrenner, Holger, Klotz, Lars-Oliver
Format: Artigo
Language:Inglês
Published: Elsevier 2016
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Research Paper
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5228094/
https://ncbi.nlm.nih.gov/pubmed/28086197
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.redox.2016.12.003
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