The transcription factor EPAS1 links DOCK8 deficiency to atopic skin inflammation via IL-31 induction

Mutations of DOCK8 in humans cause a combined immunodeficiency characterized by atopic dermatitis with high serum IgE levels. However, the molecular link between DOCK8 deficiency and atopic skin inflammation is unknown. Here we show that CD4(+) T cells from DOCK8-deficient mice produce large amounts...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:Nat Commun
Main Authors: Yamamura, Kazuhiko, Uruno, Takehito, Shiraishi, Akira, Tanaka, Yoshihiko, Ushijima, Miho, Nakahara, Takeshi, Watanabe, Mayuki, Kido-Nakahara, Makiko, Tsuge, Ikuya, Furue, Masutaka, Fukui, Yoshinori
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2017
Assuntos:
Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5228069/
https://ncbi.nlm.nih.gov/pubmed/28067314
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms13946
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados